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20 de Febrero: High-throughput bacterial genome sequencing: an embarrassment of choice, a world of opportunity.

Loman, N. J., Constantinidou, C., Chan, J. Z. M., Halachev, M., Sergeant, M., Penn, C. W., Robinson, E. R., et al. (2012). High-throughput bacterial genome sequencing: an embarrassment of choice, a world of opportunity. Nature reviews. Microbiology, 10(9), 599–606. doi:10.1038/nrmicro2850 Here, we take a snapshot of the high-throughput sequencing platforms, together with the relevant analytical…
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20 de febrero: A primer on metagenomics.

Wooley, J. C. J., Godzik, A., & Friedberg, I. (2010). A primer on metagenomics. PLoS computational biology, 6(2), e1000667. doi:10.1371/journal.pcbi.1000667 Metagenomics is a discipline that enables the genomic study of uncultured microorganisms. Faster, cheaper sequencing technologies and the ability to sequence uncultured microbes sampled directly from their habitats are expanding and transforming our view of…
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20 de Febrero: The importance of metagenomic surveys to microbial ecology: or why Darwin would have been a metagenomic scientist.

Gilbert, J. a, O’Dor, R., King, N., & Vogel, T. M. (2011). The importance of metagenomic surveys to microbial ecology: or why Darwin would have been a metagenomic scientist. Microbial informatics and experimentation, 1(1), 5. doi:10.1186/2042-5783-1-5 ABSTRACT: Scientific discovery is incremental. The Merriam-Webster definition of ‘Scientific Method’ is «principles and procedures for the systematic pursuit…
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18 de Febrero: Understanding the evolutionary relationships and major traits of Bacillus through comparative genomics.

Alcaraz, L.D., et al. (2010). Understanding the evolutionary relationships and major traits of Bacillus through comparative genomics. BMC genomics, 11(1), 332. doi:10.1186/1471-2164-11-332 BACKGROUND:The presence of Bacillus in very diverse environments reflects the versatile metabolic capabilities of a widely distributed genus. Traditional phylogenetic analysis based on limited gene sampling is not adequate for resolving the genus…
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18 de Febrero: Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial “pan-genome”.

Tettelin, H., Masignani, V., Cieslewicz, M. J., Donati, C., Medini, D., Ward, N. L., Angiuoli, S. V, et al. (2005). Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial “pan-genome”. Proc Natl Acad Sci U S A, 102(39), 13950–13955. Retrieved from http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16172379 The development of efficient and inexpensive genome sequencing methods…
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18 de Febrero: Prokaryotic taxonomy and phylogeny in the genomic era: advancements and challenges ahead.

Konstantinidis, K. T., & Tiedje, J. M. (2007). Prokaryotic taxonomy and phylogeny in the genomic era: advancements and challenges ahead. Current opinion in microbiology, 10(5), 504–9. doi:10.1016/j.mib.2007.08.006 Advancing prokaryotic taxonomy constitutes a contemporary academic challenge as well as practical necessity. Genome sequencing has greatly facilitated the evaluation of the current taxonomic system and the development…
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13 de Febrero: The Neolithic revolution of bacterial genomes.

Mira, A., Pushker, R., & Rodriguez-Valera, F. (2006). The Neolithic revolution of bacterial genomes. Trends Microbiol, 14(5), 200–206. Retrieved from http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16569502 Current human activities undoubtedly impact natural ecosystems. However, the influence of Homo sapiens on living organisms must have also occurred in the past. Certain genomic characteristics of prokaryotes can be used to study the…
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13 de febrero: Deletional bias and the evolution of bacterial genomes

Mira, A., Ochman, H., & Moran, N. A. (2001). Deletional bias and the evolution of bacterial genomes, 17(10), 589–596. Retrieved from http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11585665 Although bacteria increase their DNA content through horizontal transfer and gene duplication, their genomes remain small and, in particular, lack nonfunctional sequences. This pattern is most readily explained by a pervasive bias towards…
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13 de Febrero: Comparative genomics of gene-family size in closely related bacteria.

Pushker, R., Mira, A., & Rodriguez-Valera, F. (2004). Comparative genomics of gene-family size in closely related bacteria. Genome Biol, 5(4), 0. Retrieved from http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15059260 BACKGROUND: The wealth of genomic data in bacteria is helping microbiologists understand the factors involved in gene innovation. Among these, the expansion and reduction of gene families appears to have a…
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11 de Febrero: Niches and distributional areas: concepts, methods, and assumptions

Soberón, J., & Nakamura, M. (2009). Niches and distributional areas: concepts, methods, and assumptions. Proceedings of the National …. Retrieved from http://www.pnas.org/content/106/suppl.2/19644.short Abstract: Estimating actual and potential areas of distribution of species via ecological niche modeling has become a very active field of research, yet important conceptual issues in this field remain confused. We argue…
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11 de Febrero: Gini in the bottle

Naeem, S. (2009). Gini in the bottle. Nature, 458(April), 2–3. An elaborate microcosm study has a message for the wider world: declining distributional equity among species, where the rare become rarer, and the dominant become more dominant, can put ecosystems at risk…

11 de febrero: What is microbial community ecology?

Konopka, A. (2009). The ISME journal, 3(11), 1223–30. doi:10.1038/ismej.2009.88 The activities of complex communities of microbes affect biogeochemical transformations in natural, managed and engineered ecosystems. Meaningfully defining what constitutes a community of interacting microbial populations is not trivial, but is important for rigorous progress in the field. Important elements of research in microbial community ecology…
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Clase 6 de febrero: The merging of community ecology and phylogenetic biology.

Cavender-Bares, J., Kozak, K. H., Fine, P. V. a, & Kembel, S. W. (2009). The merging of community ecology and phylogenetic biology. Ecology letters, 12(7), 693–715. doi:10.1111/j.1461-0248.2009.01314.x Abstract The increasing availability of phylogenetic data, computing power and informatics tools has facilitated a rapid expansion of studies that apply phylogenetic data and methods to community ecology.…
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Clase 6 de febrero: Travel, sex, and food: what’s speciation got to do with it?

Souza, V., Eguiarte, L. E., Travisano, M., Elser, J. J., Rooks, C., & Siefert, J. L. (2012). Travel, sex, and food: what’s speciation got to do with it? Astrobiology, 12(7), 634–40. doi:10.1089/ast.2011.0768 Abstract We discuss the potential interactions among travel (dispersal and gene flow), bacterial ‘‘sex’’ (mainly as hori- zontal gene transfer), and food (metabolic…
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Clase 6 de Febrero: Origins. On the origin of ecological structure.

Stokstad, E. (2009). Origins. On the origin of ecological structure. Science (New York, N.Y.), 326(5949), 33–5. doi:10.1126/science.326_33 ON 23 JUNE 1802, PRUSSIAN NATURALIST Alexander von Humboldt attempted to reach the summit of Mount Chimborazo, the highest peak in the northern Andes. Bleeding, his beard caked with ice, the 33-year-old Humboldt worked his way along a…
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